# United States tariff line 2933.59.21.00: Antihistamines, including those principally used as anti-nauseants > In the United States tariff, line 2933.59.21.00 covers compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, drugs, aromatic or modified aromatic, antihistamines, including those principally used as anti-nauseants. The general (MFN) duty rate is 6.5%. It falls under HS subheading 2933.59 in heading 29.33 (chapter 29). Source: https://border.bot/countries/united-states/hs-codes/2933592100 Last updated: 9 October 2026 [Countries](https://border.bot/countries) / [United States](https://border.bot/countries/united-states) / [Chapter 29](https://border.bot/countries/united-states/hs-codes/29) / [2933.59](https://border.bot/countries/united-states/hs-codes/293359) / [2933.59.21.00](https://border.bot/countries/united-states/hs-codes/2933592100) ## Key facts - Tariff line: 2933.59.21.00 - Covers: Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, drugs, aromatic or modified aromatic, antihistamines, including those principally used as anti-nauseants - Duty (MFN): 6.5% - Preferential rates: From free (17 programmes or origins) - Additional duties: None recorded - Restrictions: None recorded - Tariff: [United States](https://border.bot/countries/united-states) - HS subheading: [2933.59](https://border.bot/hs-codes/293359) ## What this line covers In the United States tariff, line 2933.59.21.00 covers compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, drugs, aromatic or modified aromatic, antihistamines, including those principally used as anti-nauseants. Its legal text is “Antihistamines, including those principally used as anti-nauseants”, read under “Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure”, “Other”, “Drugs” and “Aromatic or modified aromatic”. ## How it is structured It falls under HS subheading 2933.59 in heading 29.33 (chapter 29). The first six digits are the Harmonized System code; the 4 digits after them are added by the United States tariff. - Chapter 29: Organic chemicals - Heading 29.33: Heterocyclic compounds with nitrogen hetero-atom(s) only - Subheading 2933.59: Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure - Within the subheading: Other - Within the subheading: Drugs - Within the subheading: Aromatic or modified aromatic - Line 2933.59.21.00: Antihistamines, including those principally used as anti-nauseants ## Duty The general (MFN) duty rate is 6.5%. Duty-free entry applies to goods that qualify under 16 programmes, and to goods from a group of origins (origin group A+). - Free: a group of origins (origin group A+) (A+) - Free: United States-Australia Free Trade Agreement (AU) - Free: United States-Bahrain Free Trade Agreement Implementation Act (BH) - Free: United States-Chile Free Trade Agreement (CL) - Free: United States-Colombia Trade Promotion Agreement Implementation Act (CO) - Free: African Growth and Opportunity Act (D) - Free: Caribbean Basin Economic Recovery Act (E) - Free: United States-Israel Free Trade Area (IL) - Free: United States-Jordan Free Trade Area Implementation Act (JO) - Free: United States-Korea Free Trade Agreement Implementation Act (KR) - Free: United States-Morocco Free Trade Agreement Implementation Act (MA) - Free: United States-Oman Free Trade Agreement Implementation Act (OM) - Free: Dominican Republic-Central America-United States Free Trade Agreement (P) - Free: United States-Panama Trade Promotion Agreement Implementation Act (PA) - Free: United States-Peru Trade Promotion Agreement Implementation Act (PE) - Free: United States-Mexico-Canada Agreement (S) - Free: United States-Singapore Free Trade Agreement (SG) ## In other countries No other national tariff on border.bot has live lines under 2933.59 yet. - [The Harmonized System text for 2933.59](https://border.bot/hs-codes/293359) ## Other lines under 2933.59 - [2933.59.10.00](https://border.bot/countries/united-states/hs-codes/2933591000) Herbicides - [2933.59.15.00](https://border.bot/countries/united-states/hs-codes/2933591500) Other - [2933.59.18.00](https://border.bot/countries/united-states/hs-codes/2933591800) Other - [2933.59.22.00](https://border.bot/countries/united-states/hs-codes/2933592200) Nicarbazin; and Trimethoprim - [2933.59.36.00](https://border.bot/countries/united-states/hs-codes/2933593600) Other - [2933.59.46.00](https://border.bot/countries/united-states/hs-codes/2933594600) Antidepressants, tranquilizers and other psychotherapeutic agents - [2933.59.53.00](https://border.bot/countries/united-states/hs-codes/2933595300) Other - [2933.59.59.00](https://border.bot/countries/united-states/hs-codes/2933595900) Other - [2933.59.70.00](https://border.bot/countries/united-states/hs-codes/2933597000) Products described in additional U.S. note 3 to section VI - [2933.59.80.00](https://border.bot/countries/united-states/hs-codes/2933598000) Other - [2933.59.85.00](https://border.bot/countries/united-states/hs-codes/2933598500) 2-Amino-4-chloro-6-methoxy pyrimidine; 2-Amino-4,6-di methoxy pyrimidine; and 6-Methyl uracil - [2933.59.95.00](https://border.bot/countries/united-states/hs-codes/2933599500) Other - Previous line: [2933.59.18.00](https://border.bot/countries/united-states/hs-codes/2933591800) Other - Next line: [2933.59.22.00](https://border.bot/countries/united-states/hs-codes/2933592200) Nicarbazin; and Trimethoprim ## Frequently asked questions ### What does tariff line 2933.59.21.00 cover in the United States tariff? In the United States tariff, line 2933.59.21.00 covers compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, drugs, aromatic or modified aromatic, antihistamines, including those principally used as anti-nauseants. ### What is the general (MFN) duty on 2933.59.21.00 in the United States? The general (MFN) duty rate is 6.5%. ### Which preferential rates apply to 2933.59.21.00? Duty-free entry applies to goods that qualify under 16 programmes: the United States-Australia Free Trade Agreement, the United States-Bahrain Free Trade Agreement Implementation Act, the United States-Chile Free Trade Agreement, the United States-Colombia Trade Promotion Agreement Implementation Act, African Growth and Opportunity Act, Caribbean Basin Economic Recovery Act, the United States-Israel Free Trade Area, the United States-Jordan Free Trade Area Implementation Act, the United States-Korea Free Trade Agreement Implementation Act, the United States-Morocco Free Trade Agreement Implementation Act, the United States-Oman Free Trade Agreement Implementation Act, the Dominican Republic-Central America-United States Free Trade Agreement, the United States-Panama Trade Promotion Agreement Implementation Act, the United States-Peru Trade Promotion Agreement Implementation Act, the United States-Mexico-Canada Agreement and the United States-Singapore Free Trade Agreement, and to goods from a group of origins (origin group A+). ## Sources and updates The tariff lines for the United States come from border.bot release 1 (edition 2026HTSRev21), read from the publisher’s files, and have been live since 9 October 2026. The duty rates for the United States come from border.bot release 1 (edition 2026HTSRev21), read from the publisher’s files, and have been live since 9 October 2026. The trade programmes for the United States come from border.bot release 1 (edition 2026HTSRev21), read from the publisher’s files, and have been live since 9 October 2026. This page was last updated on 9 October 2026. Guidance from published tariff data, not a binding ruling. For a decision customs must follow, apply to the destination’s customs authority for a binding tariff ruling. Official source files: - https://hts.usitc.gov/reststop/exportList?from=0000000000&to=9999999999&format=CSV&styles=false Machine-readable: https://border.bot/countries/united-states/hs-codes/2933592100.json